Basic Science Seminar - Targetable pathways in liver disease: Identifying targetable pathways in liver disease

 General hepatology
 Basic and translational science
 Webcasted session

North 1
English
Basic science seminar
11 April 2018 11:30 - 13:30

This session focuses on how to identify ‘targetable pathways’, with the first lecture will cover ‘Big Data Approaches’.  Moving to single cells as opposed to whole tissues, this lecture will be followed by a series of short presentations focused on novel approaches for reclassification of the immune system and its relevance in liver disease.  We will then turn to cellular metabolism and hear about how to tackle the identification of novel targets within this field.  The session will be rounded off by a talk on cell-cell interactions, focused on the imaging of communication. 

Presentations

Big data approaches to identify targetable pathways in liver cancer
Josep M. Llovet , United States
11 April 2018 11:30 - 12:00

Reclassifying immunology by single-cell approaches: Lecture
Shalev Itzkovitz , Israel
11 April 2018 12:00 - 12:10

Paired-cell sequencing reveals zonation of non-parenchymal liver cells
Keren Bahar Halpern , Israel
11 April 2018 12:10 - 12:20

Insights and therapeutic implications of single cell analysis of tumor endothelial cell metabolic signatures
To be confirmed
11 April 2018 12:20 - 12:30

How to identify new drug targets in cellular metabolism: Discussion
11 April 2018 12:30 - 12:40

Imaging of cell-cell communication
Gustavo Menezes , Brazil
11 April 2018 12:40 - 12:50

Combination of in vivo imaging and functional analysis reveals major changes in liver immunometabolic profile during newborn development
Brenda Nakagaki , Brazil
11 April 2018 12:50 - 13:00

Phagocyte network within different liver compartments: Discussion
11 April 2018 13:00 - 13:10