Symposium: Extracellular vesicles and signal transmission

 General hepatology
 Basic and translational science

West 1
English
Symposium
13 April 2018 14:00 - 15:30

Extracellular Vesicles (EVs) are released from activated cells as plasma membrane derived vesicles, known as large EVs or microvesicles and endosome derived vesicles, known as small EVs or exosomes. These vesicles carry some of the function of their donor cells and contain various proteins, mRNA and miRNA. EVs are able to deliver these content to distant cells influencing target cell function and thereby representing an important route in cell-cell communication. Increasing evidence suggests their contribution to tumor growth, angiogenesis and regulation of immune and inflammatory responses. Moreover, EVs present in various tissue fluids can be used as biomarkers and provide a novel tool for therapeutic intervention.
The symposium will explore the current understanding of EVs in various liver injuries such as alcoholic liver damage, non-alcoholic steatohepatitis (NASH) and cholangiopathy. Moreover, it highlights the potential use of EVs in diagnostic classification of liver disorders.


Presentations

Extracellular vesicles in NASH
Ariel Feldstein , United States
13 April 2018 14:00 - 14:20

Extracellular vesicles in cholangiopathy
Jesus M. Banales , Spain
13 April 2018 14:20 - 14:40

Exosomes in alcoholic liver disease
Gyongyi SZABO , United States
13 April 2018 14:40 - 15:00

Microvesicles as novel diagnostic tools for HCC and CCA
Miroslaw Kornek , Germany
13 April 2018 15:00 - 15:20

Disucssion
13 April 2018 15:20 - 15:30