Meet the Expert: Management of autoimmune hepatitis

 Cholestasis and autoimmune

West 4
English
Meet the Experts
12 April 2018 08:30 - 09:20

Questions for discussion: 
1. Goals of therapy: Definition of responders and non-responders
2. What is the role of liver biopsy and histology in the management of AIH
3. Can we agree on remission rates for first line therapies ? 25 %, 50 %, 80 %, 100 % ?
4. Second line therapies for non-responders ?
5. Second line therapies for patients intolerant to standard of care (SOC)
6. What is the role of biologicals in the management of autoimmune hepatitis: anti TNF ? , rituximab ? anti CD 3 ? ongoing trials with novel agents ?
7. Experimental therapies – in humans ? cellular therapies ? T regs ?
8. Role of liver transplantation in 2018
9. Is natural course and management of AIH different in children and adolescents ?
10. End points and design of clinical trials in autoimmune hepatitis